Holy shit WTF Antihistamines!!!

  1. YES. I just had the BEST period of my life and I took Benadryl every night, and did a low histamine diet - no dairy, tomatoes, avocado, alcohol is what I cut out. I haven’t been bloated, and I took no pain meds during my two days where I’m usually in uncontrollable pain from cramps. IVE BEEN SHOUTING FROM THE ROOFTOPS ABOUT THIS.

  2. I can sympathize. 💖💜 I really wish loratadine did shit for me. 😒 I think I am literally allergic to Florida or some places, 'cause I remember taking a trip as a teen or pre-teen and could NOT BREATHE, or stop goddamn sneezing the ENTIRE TIME I was there. My dad (who's also a pharmacist) got me Claritin, and it did absolutely nothing for me.

  3. Try H2 antihistamines, thats what famitodine is. They work on differnet histamine receptors, thatnis why so many people try them and they dont work, you have to try both types. I take both H1 and H2 type. Hang in there 💕

  4. I'm glad you're feeling better, but as a lifelong year round allergy suffer, you will need to be mindful about taking 2 loratadine like you are.

  5. My bottle of loratidine says 10mg/24hours. Is what you’re doing safe? Besides/regardless, I keep seeing these posts and hope antihistamines can be researched for PMDD. It’s awesome and exciting and I’m pretty sure related to how they were used for schizophrenic patients in the 50s. Take care🙏👍.

  6. Loratidine 10mg also has some doperminergic action - it won't make you clean the house but it can help you focus slightly better if you're having a struggle. I have ADHD but I noticed a difference adding it to my med regime - not extra energy, just some more quiet focus. Anecdotal in terms of personal effect but I found out about the potential action via some pharmaceutical research.

  7. I’ve tried Benadryl, Hydroxyzine and Loratidine. Currently taking Loratidine because of spring allergies. They all work wonders. I’d take Benadryl or hydroxyzine at night if I can’t sleep.

  8. Taking Benadryl to help sleep is what I did last month and I was really surprised by how mild my pmdd symptoms were. I didn’t take it for that, but it was a great side effect.

  9. Same. I took zyrtec and pepcid. Pepcid is the recent add-on that made the difference. I was a little more tired but nothing extra caffeine can’t handle. I’ll take that over the other any day

  10. First time taking it this month, it worked. My breasts weren’t sore either; I don’t know if that’s why but I’m not looking this gift horse in the mouth.

  11. Cetirizine is the only one that works for me. It was the only one that ever helped my allergies. I definitely notice huge improvement in symptoms. I posted about it, but mods take down antihistamine posts a lot. You aren't allowed to talk about medication that is taken against the original way intended or whatever. But I take Zyrtec everyday for my allergies and it definitely helps with my PMDD. There were a few months where I didn't, and the difference was insane.

  12. Really? Thats so strange because Im in NZ and the antihistamines Ive been prescribed - famitodine and loratidine were both prescribed for PMDD. I discussed it with my GP and she approved it all. Doctors often prescribe things for off label use, its not illegal to do so, it seems really unfortunate if posts like this get taken down.

  13. I’ve been using be Benadryl at night (cycle day 24 on a 26 cycle) and holy shit, I am a different person. My husband was shocked to come home and find me cleaning up and in a good mood. Usually I have like a heavy pressure all over my body, weird feeling in my nose, a heavy chest, sore itchy throat, my face feels swollen, am exhausted and can’t think clearly.

  14. I also get a lot of itchiness, brain fog, and insomnia that often starts before ovulation already. Then I get terrible anxiety on top of that in my luteal phase. It makes me wonder if I react differently to estrogen vs progesterone.

  15. For those it worked for, how long did it take for you to notice an improvement/symptoms gone? I tried phenergan and I had a more improved sleep but that was it

  16. There are two differnet types of antihistamine - H1 and H2. I require both types to reduce my histamine enough to get the effect. Effect was obvious in a day or two.

  17. I tried a few different ones. Cetirizine was the one that actually really helped me. I also take it daily now for allergies, works wonders. It doesn't get rid of everything, but a lot of symptoms are diminished. I started taking it just after my period and my next luteal phase was much better.

  18. I had to try a few. My belief is it doesn't work for everyone, like anything else. Cetirizine was the one that really helped with my allergies and PMDD symptoms.

  19. Pretty crazy right?! This is the second cycle for me trying it and it freaking works! I just take the Costco brand kind and it works great. Interesting to see how long this lasts.

  20. I have adhd/asd and I have experimented with Benadryl during my hell weeks. It has worked. Now I’m on adderall plus Prozac only as needed during days 13-28. This month I’m trying adderall only to see if it helps my pmdd symptoms but I have a feeling it won’t.

  21. Just out of curiosity, do you happen to have ADHD? Someone told me that "antihistamines help calm catecholaminergic reaction" and when I went to look that up I found

  22. Another pmdd/ADHD sufferer here... Never tried antihistamines for hell week but this thread convinced me to try for my next cycle!

  23. I’m another woman with PMDD and adhd! I usually find my meds basically ineffective while I’m on my period but this week taking benedryl they worked way better!!!

  24. This is extremely interesting to me. I have ADHD. I was diagnosed only a few years ago. Antihistamines help me a lot. But I feel like there may also be a link between allergy sufferers and antihistamines helping. That's just a trend I noticed. I could be completely wrong.

  25. You have to find the allergy medicine that works for you. As a year round allergy sufferer, your body metabolizes the meds differently, and you will need to find one that works for you.

  26. So if I am understanding correctly, allergy medicine can help the non-physical pmdd symptoms such as my depression, sadness, ruminating thoughts, and it is possibly that I won’t have these symptoms anymore? Or is it JUST the physical symptoms of pmdd? Because I don’t have any physical symptoms

  27. Wow, I really hope this continues to work for you! I wonder if it has something to do with curbing an inflammatory response...

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